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Vitamine D deficient gelinkt aan hartfalen

15 september 2010 - Wetenschap

Adults with decreased levels of serum 25-hydroxy vitamin D are significantly more likely to die from heart failure or die prematurely, compared with adults who have normal serum levels of vitamin D, results from a large analysis found. (NHANES)

Reviewed data: 13,131 individuals (6,130 men and 7,001 women) aged 35

Vitamin D deficiency was defined as having a serum level below 20 ng/mL, while vitamin D insufficiency was defined as having a serum level ranging from 20 to 29 ng/mL. Normal levels were defined as 30 ng/mL or greater.

Premature death was defined as death before age 75 years.

Results: more than 60% of African American study participants were vitamin D deficient, compared with 20% of whites and about 40% of Hispanics.

The rate of vitamin D deficiency among heart failure deaths was 37%, compared with 26% among non-heart failure–related deaths, a difference that was statistically significant.

After the researchers adjusted for age, gender, race, and baseline medical conditions, study participants with vitamin D deficiency were 3.4 times more likely to die from heart failure, compared with those who had normal vitamin D levels, while those with vitamin D insufficiency were 2 times more likely to die from heart failure, compared with those who had normal vitamin D levels. (ACEP.News)

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